OTOTOXICITY means damage to the ear due to the toxic effects of various chemical drugs.The most ototoxic medication belongs to a class of antibiotics called Aminoglycosides, such as Amikacin .Ototoxic drugs effect both Cochlear and Vestibular parts of inner ear.Ototoxic drugs causes hearing loss by affecting the HAIRS CELL. Ototoxic drugs causes sensorineural hearing loss. It is possible for the losseventually become PROFOUND.
